Convergence Technologies has plans for what it claims is "the first, truly universal household remote"-- the Bridge, compatible with not only standard TVs and STBs, but also PCs and game consoles.
Looking like a games controller, the Bridge combines a QWERTY keyboard, an analog stick handling mouse control and x4 shoulder buttons.
Control signals come via IR and RF4CE protocol, meaning it is compatible with around 95% of TVs from the last 3 years, as well as the Playstation 3 console (Wii and XBox 360 compatibility is still pending further review).
Convergence are currently looking for development funding on Kickstarter-- and hope to raise $59000 in 45 days' time. Should funding be complete, the company will sell the Bridge for under $100.